阵列式微液滴生成芯片研究Research on Array Microdroplets Generation Chip
金少搏,叶国永,曹娜,刘旭玲
摘要(Abstract):
以构建相互独立的微液滴为基础的液滴微流控芯片,已成为生物、化学、医疗、材料制备研究的重要实验平台。微液滴的制备是液滴微流控技术的关键。为了提升微液滴的制备速率,这里设计了阵列化的微流道结构,通过仿真设计和微纳制造工艺制作了PDMS材料的微流控芯片。使用多物理场耦合仿真软件COMSOL对微液滴生成过程的进行了参数化研究,得出了微液滴大小的调控规律。通过实验进一步验证了阵列式液滴生成单元液滴生成的效果和调控规律。为进一步的阵列扩增,实现更高通量的液滴检测生成奠定了基础。
关键词(KeyWords): 微液滴;微流控;阵列;PDMS
基金项目(Foundation): 国家自然科学基金资助项目(52205607);; 河南省科技攻关项目(222102310213);; 郑州轻工业大学博士基金(2021BSJJ020)
作者(Author): 金少搏,叶国永,曹娜,刘旭玲
DOI: 10.19356/j.cnki.1001-3997.20260403.005
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